Ketocon azole

Abbas R et al (2011) Pharmacokinetics of oral neratinib during co-administration of ketocon-azole in healthy subjects. Br J Clin Pharmacol 71 522-527... 

ISONIAZID ANTI FUNG ALS -ITRACONAZOLE, KETOCONAZOLE, POSACONAZOLE, VORICONAZOLE i levels of these azoles, with significant risk of therapeutic failure Isoniazid is a known inhibitor of CYP2E1 and is likely to induce other CYP isoenzymes to varying degrees, usually in a time-dependent manner Avoid co-administration of ketocon-azole or voriconazole with isoniazid. Watch for inadequate therapeutic effects of itraconazole. Higher doses of itraconazole may not overcome this interaction, so consider the use of less lipophilic fluconazole, which is less dependent on CYP metabolism... 

Cyproterone acetate Androgen synthesis inhibition Aminoglutethimide Ketocon azole Progesterones ... 

We monitored the reproducibility for a 10 pL injection of loperamide and ketocon-azole over a 12.5 h period in both rat plasma and homogenized rat brain (diluted 1 4 with water). The results are displayed in Figure 8.7 and demonstrate the overall improved reproducibility that has been observed for UPLC. This is important for determining potential matrix effects. Improved carryover has also been observed in most cases (<0.1%) precluding the need for multiple solvent blank injections [41],... 

Shin, S., 2003. Anti-Aspergillus activities of plant essential oils and their combination effects with ketocon-azole or amphotericin B. Arch. Pharmacol. Res., 26 389-393. 

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