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Kampo medicines active compounds

The alkaloids hirsutine (1) and its 3or-epimer dihydrocorynantheine (2a) belong to the corynanthe group of indole alkaloids. They have been isolated from the plant Uncaria rhynchophylla MIQ, which was used for the preparation of the old Chinese folk medicine kampo . Nowadays, 1 and related compounds attract great attention in medicine because of their growth inhibition of the influenza A subtype H3N2 virus. With an EC50 value of 0.40-0.57 ig/mL 1 has shown itself to be 10-20 times more active than the clinically used drug ribavirine (3).1,2 Furthermore, 1 is known for its antihypertensive and antiarrhythmic activity.3... [Pg.101]

See other pages where Kampo medicines active compounds is mentioned: [Pg.239]    [Pg.603]    [Pg.175]    [Pg.876]    [Pg.890]    [Pg.898]    [Pg.925]    [Pg.182]    [Pg.183]    [Pg.473]    [Pg.338]    [Pg.876]    [Pg.906]   
See also in sourсe #XX -- [ Pg.24 , Pg.878 ]

See also in sourсe #XX -- [ Pg.878 ]



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Kampo medicine

Medicinal compounds

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