JV-Methylpyrrolidone

FIGURE 5.6 Variation of viscosity of solutions of partially chlorinated poly(l,4-phenylene-2,6-naphthalamide) dissolved in solvent mixture of hexamethylene phosphoramide and JV-methylpyrrolidone containing 2.9% Li Cl, as a function of solution concentration showing transition from isotropic to anisotropic behavior. (After Morgan, P. W. 1979. Chem. Tech., 316.)... 

The reduction of a,a -dibromo ketones in the presence of jV.A -dialkylated carboxamides generally leads to the formation of 3(2//)-furanones of type CLXXIX. A. A -Dimethylformamide, yv,A -dimethylacetamide, A. A -dimethyl-benzamide, and A -methylpyrrolidone can be used as carboxamide. A muscarine derivative (CLXXXI) has been prepared from CLXXX in several steps (Noyori et al., 1973e). 

NMP Af-methylpyrrolidone NMM JV-methylmOTpholine DMAP 4-diraethylaminopyridine Reaction conditions 17a (0.2 mmol), coupling reagents (0.4 mmol), base (0.6 mmol), solvent (2.0 ml), room temperature, 12 h Isolated yield by flash column chromatography No base is used No product can be detected... 

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