Julia synthesis allylsilanes

The Julia alkene synthesis has been applied to allylsilane synthesis, including the synthesis of 2-cyclopentylidene- and 2-cyclobutylideneethyl(trimethyl)silanes30. 

Since its original publication,94 the Julia olefination has become a very important tool in organic synthesis for the site- and stereoselective synthesis of alkenes. The synthetic importance of the process is reflected by its numerous applications in the synthesis of a diverse range of functionalized alkenes such as allylic alcohols,198 allylic amines,199-201 homoallylic alcohols,202 homoallylic amines,203 and allylsilanes.204,129 The reaction has also been used as a key step in many... 

Mediods for overcoming these difficulties include the reaction in Scheme 64 and the corresponding Julia (Scheme 76) or Krief-Reich alkene syntheses, which are all selective for the synthesis of ( )-allylsilanes. These methods use phosphorus, sulfur or selenium as the electrofugal group another possibility is to use electrofugal carbon in a decarboxylative elimination, which can be carried out stereospecifically either anti or syn (Scheme 77). ... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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