Jencks, William

The versatile chemistry of pyridoxal phosphate offers a rich learning experience for the student of mechanistic chemistry. William Jencks, in his classic text. Catalysis in Chemistry and Enzymology, writes ... 

Royal Society of Chemistry, London Page, M. I. and Jencks, W. P. (1987). Gazz. Chim. Ital. 117, 455 Page, M. I. and Williams, A. (eds) (1987). Enzyme Mechanisms. Royal Society of Chemistry, London... 

A. Williams, Concerted Organic and Bioorganic Mechanisms, CRC Press, New York, 2000. W. P. Jencks, How Does a Reaction Choose Its Mechanism , Chem. Soc. Rev. 1981,10, 345. J. P. Richard, Simple Relationships between Carbocation Lifetime and the Mechanism for Nucleophilic Substitution at Saturated Carbon, Adv. Carbocation Chem. 1989, 1, 122. T. W. Bentley and G. Llewellyn, Scales of Solvent Ionizing Power, Prog. Phys. Org. Chem. 1990, 17, 121. 

William P. Jencks, Mechanisms in Chemistry and Enzymdogy, Dover, New York, 1975. 

In 1969, the enzymologist William Jencks (Brandeis University, Waltham/MA, USA) described the possibility of causing enzyme-like catalytic effects with antibodies. 

Williams, A. and Jencks, W.P. (1974) Journal ofthe Chemical Society, Perkin Transactions 2, 1760. 

Some enzymes are so fast and so selective that their k2/Km ratio approaches the molecular diffusion rates (108-109m s-1). Such enzymes are called kinetically perfect [21]. With these enzymes, the reaction rate is diffusion controlled, and every collision is an effective one. However, since the active site is very small compared to the entire enzyme, there must be some extra forces which draw the substrate to the active sites (otherwise, there would be many fruitless collisions). The work of these forces was dubbed by William Jencks in 1975 as the Circe effect [22], after the mythological sorceress of the island of Aeaea, who lured Odysseus men to a feast and then turned them into pigs [23,24]. 

CATALYSIS IN CHEMISTRY AND ENZYMOLOGY. William P. Jencks. Exceptionally clear coverage of mechanisms for catalysis, forces in aqueous solution, carbonyl- and acyl-group reactions, practical kinetics, more. 864pp. 5X x 8H. 65460-5 Pa. 18.95... 

A History of Mechanics, Rent Dugas. (65632-2) 14.95 Catalysis in Chemistry and Enzymology, William Jencks. (65460-5) 18.95... 

The utilization of attractive forces to lure a substrate into a site in which it undergoes a transformation of structure, as defined by William P. Jencks, an enzymologist, who coined the term. 

By Lawrence Levine, Augustin Baer, and William P. Jencks... 

William P. Jencks (31), Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02154... 

This book is dedicated to William P. Jencks and the late Myron L. Bender... 

The late William Jencks of Brandeis University first proposed the theory behind FBDD 30 years ago [8] ... 

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