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Jaspamide antifungal activity

From sponges of the genus Jaspis collected at Fiji (300,301), Palau (300), and Papua New Guinea (302), jaspamide (jasplakinolide, 372) was isolated the compound shows potent insecticidal, antifungal, anthelminthic, and ichthyotoxic activity. The structure was determined by X-ray analysis (300). The solution conformation of372 was reported using NMR, molecular mechanics, and dynamics calculations (303). A complexation study was carried out with 372 and the univalent metal ions Li ", Na+, and K+. Li+ binding was observed, and the complex was characterized by NMR and molecular mechanics calculations (304). Jaspamide (372) has potent in... [Pg.95]


See other pages where Jaspamide antifungal activity is mentioned: [Pg.96]    [Pg.24]    [Pg.308]    [Pg.79]    [Pg.1277]    [Pg.757]    [Pg.768]    [Pg.150]    [Pg.51]    [Pg.99]    [Pg.207]    [Pg.485]    [Pg.103]   
See also in sourсe #XX -- [ Pg.5 , Pg.428 ]

See also in sourсe #XX -- [ Pg.5 , Pg.428 ]

See also in sourсe #XX -- [ Pg.341 ]




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Activity antifungal

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