Janssen, Paul

The Paul Janssen Professor of Translational Neuroscience (in Psychiatry and Radiology)... 

An important step for the treatment of severe pain was made in the early 1960s Paul Janssen s exploitation of 4-piperidone chemistry proved remarkably successful in that it led to the clinical use of both a major tranquilizer (haloperidol) and a potent narcotic analgesic, fentanyl. Fentanyl is related to pethidine and also to basic anilides with analgesic properties and is characterized by high potency and short duration of action. Again, a series of derivatives was synthesized over the following decades which led to several products for clinical use, however fentanyl is still very important for the treatment of severe pain. 

Mark Crane, Martien Janssen, Peter Matthiessen, Steve Maund, Graham Merrington, and Paul Whitehouse... 

The Department of Neuroscience (December 2006) Web page for the Columbia University Medical Center describes the Paul Janssen Professorship and the Paul Janssen Scholars program as resulting from a partnership between the university and Johnson 8c Johnson. It is a frightening illustration of how deeply embedded the pharmaceutical industry has become in the nation s leading medical centers. 

Department of Neuroscience. (2006). Paul Janssen Fellowship, Columbia University Medical Center. Retrieved from http //www.excalibur.cpmc.columbia.edu/about janssen.html... 

Janssen, Johannes. History of the German People at the Close of the Middle Ages. Volume XIV. Translated by A.M. Christie. Kegan Paul, Trench, Trubner Co. Ltd, London. 1909. 

Dedicated to the memory of the great medicinal chemist Dr. Paul Janssen (1926-2003), the discoverer of many breakthrough medicines. 

Dr. Paul A. J. Janssen, former Director of Janssen Pharmaceutica N. V., Beerse Belgium, and founder of the Center for Molecular Design, Vosselaar, Belgium, unexpectedly died on November 11, 2003. As he was one of the most prominent medicinal chemists and discoverer of many breakthrough medicines, the Volume and Series Editors would like to dedicate this book to the memory of this great man. 

Present address Unilever Research Laboratory Vlaardingen, Olivier van Noortlaan 120, 3133 AT Vlaardingen, The Netherlands, e-mail Jean-Paul.Janssens Unilever.com... 

Paul Janssen, Private Communication, Eupharma-Ned-Chem Pharmaceutical Laboratories. 

Figure 45 Spectral mapping diagram of neuroleptic drugs. Circles represent the compounds and squares the different test models. The sizes of the symbols indicate the relative activities of the drugs and the sensitivities of the test models numbers refer to Figure 3 of ref. [802] (diagram provided by courtesy of Dr. Paul Lewi, Janssen Pharmaceutica, Beerse, Belgium).

Dr. Paul Janssenweg 150,5026 RH Tilburg, The Netherlands (Tel 3113 583 7373 FAX 31135837300 E-mail Jcinfo Jacnl.JnJ.com Internet www.Janssen-cilag.nO... 

In the 1950s, the first medicines for treatment of mental illness reached the market. Paul Janssen had developed haloperidol for treatment of schizophrenia, and Geigy introduced imipramine as a therapy for depression. Thereby, for the first time these widespread and serious illnesses could be managed successfully. Patients, who had previously been admitted to mental institutions on a routine basis, were now able to live on in their familiar surroundings. 

Pescarmona PP, Janssen KPE, Delaet C, Stroobants C, Houthoofd K, Philippaerts A, De Jonghe C, Paul JS, Jacobs PA, Sels BF (2010) Zeolite-catalysed conversion of C3 sugars to alkyl lactates. Green Chem 12 1083-1089... 

Janssen KPF, Paul JS, Sels BE, Jacobs PA (2007) Glyoxylase biomimics zeolite catalyzed conversion of tiioses. Stud Surf Sci Catal 170B 1222—1227... 

Paul, J.S., Janssens, R., Denayer, J.F.M., Baron, G.V. and Jacobs, P.A. (2005). Optimization of MoVSb oxide catalyst for partial oxidation of isobutane by combinatorial approaches, J. Comb. Chem., 8, 407-413. 

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