James I

Huffman, William H. and Robert A. Seelinger. Robert Fludd s "Declaratio Brevis" to James I. Ambix 25 69-92. 

Smoking tobacco in pipes for pleasure... was made socially acceptable by Sir Walter Raleigh. Many, however, thought it disgusting and the use of tobacco in this way was virulently attacked. The opposition was led by James I in 1603, and he published a pamphlet... 

Walker, J. B., Hughes, B., James, I., Haddock, R, Kluft, C., Bajzar, L. (2003). Stabilization versus inhibition of TAFIa by competitive inhibitors in vitro. J. Biol. Chem., 278, 8913-8921. 

The first British settlement in North America was established in 1607 and named Jamestown, after King James i. The little tobacco-growing colony was located on the East Coast, in the region that would eventually become the state of Virginia. One of the constant debates among the Jamestown settlers was whether they should expand the colony. Tobacco growing was a very profitable enterprise, especially since labor was so cheap — the Jamestown settlers had brought the first African slaves to North America. But the settlement was surrounded by unfriendly Indians who would, of course, resist the expansion. 

King James I of England expresses a rather different opinion in his Counterblast to Tobacco, which denies the substance has any real medicinal value. The king also tries to reduce the growing popularity of smoking by taxing tobacco, a practice that is soon taken up by other European nations. 

Lloyd, R.S., Costello, F., Eves, M.J., James, I.G., Miller, A.J. The efficacy and tolerability of controlled-release dihydrocodeine tablets and combination dextropropoxyphene/paracetamol tablets in patients with severe osteoarthritis of the hips, Curr. Med. Res. Opin. 1992, 13, 37-48. 

Winter, J., Walpole, C.S., Bevan, S., James, I.F Characterization of resiniferatoxin binding sites on sensory neurons co-regulation of resiniferatoxin binding and capsaicin sensitivity in adult rat dorsal root ganglia, Neuroscience 1993, 57, 747-757. 

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