Isozymes F-III

All the isozymes have a lot of overlapping identical residues and some regions of the sequences show similar characteristics to serine-like proteases, such as elastase and coagulation factor IX. The N-terminal sequences of F-III-1 and -III-2 are identical, and so are those of F-I-l and F-I-2, respectively. So far, several complete reading frames (amino acid sequences) of the isozymes, F-III-1 and -III-2 (L. rubellus) [24,28], EFE... 

So far, a few of isozymes (F-III-1, III-2 and -II, etc) have been purified and studied in detail. Some molecular and pharmacological properties of EFEs are still unclear. However, EFEs are usefully investigated as a candidate to therapies for diabetes, anti-fat crystallization, blood pressure adjuster (hypertension and hypotension), solvent thrombus, cerebral vessels, angina, liver disorder, cataracts, glaucoma, varicosity, rheumatism, bedsores, nephritis, vibration disease, etc [91-100]. These would be meaningful topics for further studies. 

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See also in sourсe #XX -- [ , , , ]

See also in sourсe #XX -- [ , , ]

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