Isothiocyanato

In a similar way the use of the 2-methyl-3-isothiocyanato-4-thiocyanato-hept-3-ene (252) prepared from thiocyanogen and the oxoal-kylene phosphorane (251) yields the 2-anilino-4-propyl-5-isopropyl-thiazole (253) by condensation with aniline (Scheme 128). 

Isothiocyanato-3,3-dimethylbutan-2-one (87) provided the C4N3 fragment that gave, upon reaction with 2-ethylthiosemicarbazide (CN3 fragment) (88), the 3-ethyl-l,6,7,8a-tetrahydro-2,5-dithioxo-8,8,8a-trimethyl-l,2,4-triazolo[l,5-c]pyrimidine 89 (76M1241) (Scheme 33). 

Most of the reactions applied to amines can also be transferred to alcohols (Eig. 7-5). One large group of chiral alcohols are the (i-adrenoreceptor blockers, for which a variety of derivatization agents was developed. One highly versatile reagent for the separation of (i-blockers is A-[(2-isothiocyanato)cyclohexyl]3,5-dinitrobenzoyl-amide (DDITC) [11]. Alternatively, unichiral drugs such as (3-blockers or (S)-naproxen [12] may be used in a reciprocal approach to derivatize racemic amine compounds. 

Chromium, bis(l,2-ethanediamine)difluoro-photochemistry, 1,393 Chromium, bis(l, 2-ethanediamine)oxalato-coordination isomerism, 1, 183 Chromium, diamminetetrakis(isothiocyanato)-photoaquation chemical actinometer. 1,409 photochemistry reactivity, 1, 398... 

Cobalt, bis(dimethy glyoxime)isocyano-, 1, 186 Cobalt, bis(l,2-ethanediamine)bis(isothiocyanato)-chloride... 

Nitro-l-isothiocyanato-benzol wird reduktivzu2-Mercapto-benzimidazol-3-oxid cy-clisiert3 ... 

Anhydro-a-D-fructofuranose P-D-fructopyranose l,2 2,l -dianhydride (55) 6-Deoxy-6-isothiocyanato-a-D-fructofuranose P-D-fructopyranose 1,2 2,1 -dianhydride (56) 6-Deoxy-6-iodo-a-D-fructofuranose 6-deoxy-6-iodo-p-D-fructofuranose 1,2 2,1 -dianhydride (57) 6-Chloro-6-deoxy-a-D-fructofuTanose 6-chloro-6-deoxy-P-D-fructofuranose 1,2 2,1 -dianhydride (58) 6-S-Heptyl-6-thio-a-D-fruclofuranose 6-S-heptyl-6-thio-p-D-fructofuranose 1,2 2,1 -dianhydride (59) 6-Azido-6-deoxy-a-D-fructofuranose 6-azido-6-deoxy-P-D-fructofuranose 1,2 2,l -dianhydride (60) 6-Amino-6-deoxy-a-D-fructofuranose 6-amino-6-deoxy-p-D-fructofuranose 1,2 2,1 -dianhydride (61) 6-Acetamido-6-deoxy-[Pg.260]

The N-oxide of l-pyrrolo[2,3-b]pyridine 936 is converted by the combination tri-methylsilylisothiocyanate Me3SiNCS 937/MeOCOCl to 21% 6-isothiocyanato-l-methoxycarbonyl-pyrrolo[2,3-b]pyridine 938 and 18% 6-chloro-l-methoxycarbonyl-pyrrolo[2,3-F]pyridine 939 [51] (Scheme 7.14). To avoid formation of the chloro compound 939 a reagent combination of MesSiNCS 937 with triethylamine or DBU, which lacks any competing chloride ion, might give much higher yields of... 

Functionalized silacyclobutanes 16 result from photochemical decomposition of [azido-, isocya-nato- and isothiocyanato-bis(tert-butyl)silyl]diazoacetates 15. They undergo a remarkably facile ring-expansion reaction to cyclic O-silyl ketene acetals 17 even at 60°C. 

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