Isotachophoresis polymers

Khan, K., Van Schepdael, A., Saison-Behmoaras, T., Van Aerschot, A., and Hoogmartens, J. (1998). Analysis of antisense oligonucleotides by on-capillary isotachophoresis and capillary polymer sieving electrophoresis. Electrophoresis 19, 2163-2168. 

Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T., Determination of inorganic selenium species by miniaturised isotachophoresis on a planar polymer chip. Anal. Bioanal. Chem. 2003, 376, 78-84. 

Isotachophoresis (ITP) offers cm alternative to these chromatographic methods for the separation and chemical characterization of high-moleculeur-weight synthetic polymers containing an lonlzed)le functional group. The separations occur because of differences in the effective electrophoretic mobilities of the macromolecules. 

On the other hand, two promising techniques that are rapidly gaining interest, namely isotachophoresis (ITP) and HPLC, are less common in standard polymer characterization. Recently, FTP has been shown to be a powerful tool in oligomer analysis, and at present HPLC is being developed for that purpose. Therefore, the latter more specific methods will be briefly discussed first. 

S.J. Baldock, P.R. Fielden, N.J. Goddard, J.E. Prest, B.J. Treves Brown, Integrated moulded polymer electrodes for performing conductivity detection on isotachophoresis microdevices. Journal of Chromatography A 990 (1-2) (March 2003) 11-22. 

Tribet, C., R. Gaboriaud, R Gareil, Analogy between micelles and polymers of ionic surfactants. Capillary isotachophoresis study of small ionic aggregates in water-organic solutions, J. Chromatogr., 1992, 60S, 131-141. 

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