Isoamyl carbamate

Methylbutyl acetate, see sec-Amyl acetate 3-Methylbutyl acetate, see Isoamyl acetate 3-Methyl-l-butyl acetate, see Isoamyl acetate 3-Methylbutyl ethanoate, see Isoamyl acetate Methylbutyl ethyl ketone, see 5-Methyl-3-heptanone Methyl n-butyl ketone, see 2-Hexanone Methylcarbamate-l-naphthalenol, see Carbaryl Methylcarbamate-l -naphthol, see Carbaryl Methyl carbamic acid, 2,3-dihydro-2,2-dimethyl-7-... 

Diazotisation of ketoxime carbamates 254 in concentrated sulfuric acid with either isoamyl nitrite or sodium nitrite leads to the Beckmann rearrangement products in moderate to excellent yields with CO2 and N2 as the only by-products " (equation 76). 

Other carbamates such as ethyl-n-propyl, isopropyl, 3-butyl, isobutyl, sec-butyl, n-amyl, isoamyl, 2-methylbutyI, 1-ethylpropyl, and 2-ethylhexyl carbamate were prepared in a manner similar to that described here for 2-ethylbutyl carbamate in 55-76 % yields [19]. Benzyl carbamate has also been reported to be prepared by this method in 91-94% yield [17]. 

A synthesis of 3 starting from a conformationally flexible D-mannitol A-Boc bis-aziridine derivative 81 has been reported (Scheme 14). The cyclic carbamate-protected pyrrolidine 82 was obtained from 81 via the regioselective bis-aziridine ring opening with Li2NiBr4, followed by Ag+-promoted intramolecular substitution of the bromide by the N -Boc group in 75% overall yield. Nitrous acid deamination of 82 with isoamyl nitrite led, in 50% yield, to a 1 1 mixture of cyclic carbamate protected pyrrolidines 84 and 85 via the intermediate... 

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