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Ischemic heart disease gene therapy

It is obvious that angiogenic therapy for ischemic heart disease using gene therapy, cell transplantation, and hematogenous cytokine administration will benefit increasing numbers of patients. However, long-term studies monitoring side effects to... [Pg.294]

A confluence of scientific, technical, and medical advancements has made genetic therapeutics for cardiovascular disease a promising and exciting field. The molecular mechanisms of major cardiovascular disorders such as atherosclerosis, ischemic heart disease, and myocardial failure have been well characterized. Sophisticated surgical and catheter-based systems that can enable the delivery of therapeutic genes or cells in vivo are in clinical use, and clinical therapeutic end-points for the evaluation of treatment efficacy have been clearly defined. Simultaneously, gene therapy has evolved from a modality restricted to the potential cure of monogenetic diseases to a therapeutic platform that enables cus-... [Pg.316]

Kapur, N. K. and Rade, J. J. 2008. Fibroblast growth factor 4 gene therapy for chronic ischemic heart disease. Trends in Cardiovascular Medicine, 18,133-141. [Pg.368]

See other pages where Ischemic heart disease gene therapy is mentioned: [Pg.31]    [Pg.37]    [Pg.130]    [Pg.138]    [Pg.228]    [Pg.460]    [Pg.460]    [Pg.461]    [Pg.364]    [Pg.290]    [Pg.290]    [Pg.315]    [Pg.166]    [Pg.235]    [Pg.1312]    [Pg.454]   
See also in sourсe #XX -- [ Pg.284 ]



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Ischemic

Ischemic disease

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