Iodized ethyl ester

By interfering with absorption, intestinal parasitic infestation reduces the efficacy of oral supplementation with iodized ethyl esters. 

In an intervention study with schoolchildren 8—10 years old in Malawi, Furnee et al. (1997) examined the relationship of intestinal parasite treatment and oral iodized oil efficacy. Severely iodine-deficient schoolchildren with a single parasitic infestation, either A. lumbricoides (n = 44), hookworm (n = 42), or Entamoeba histolytica (n = 24), were randomly allocated to receive or not receive treatment before taking a 1ml oral supplement (490 mg Iodine) of iodized ethyl esters from poppyseed oil. After supplementation, urinary iodine concentrations were measured regularly, to define time intervals indicating moderate iodine deficiency before urinary iodine concentrations returned to 0.40 mmol/1. Treatment with metronidazole for E. histolytica increased the protection period from 2.0 to 21.0 weeks P < 0.05). For all untreated children, the duration effect was 9.2 weeks shorter P < 0.001) than for their treated peers (16.8 weeks). They concluded that, by interfering with absorption, intestinal parasitic infestations reduce the efficacy of oral supplementation with iodized ethyl esters (Table 52.8). 

Due to the radio-opacity of the Iodized Ethyl Esters, it can be used with NBCA without the use of an opacifying agent unless the NBCA concentration is over 50% of the mixture. In those cases Tantalum powder is recommended using 1 gram for every 1 cc of NBCA. Before the injection of the NBCA mixture, a 5% dextrose solution should be used to rinse the catheter. This will prevent the NBCA to solidify before reaching the targeting tis-... 

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