Intrinsic signal optical imaging

Suprathreshold auditory cortex activation visualized by intrinsic signal optical imaging. Cereb Cortex 6 120-130. 

Masino SA, Kwon MC, Dory Y, Frostig RD. 1993. Characterization of functional organization within rzit barrel cortex using intrinsic signal optical imaging through a thinned skull. Proc Natl Acad Sci USA 1993 Nov 1 90(21) 9998-10002. 

Grinvald A, Lieke E, Frostig RD, Gilbert CD, Wiesel TN. 1986. Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature 324 361-364. 

Hard N, Mori N, Sawada S, Mount RJ, Harrison RV. 2000. Three distinct auditory areas of cortex (AI, All, and AAF) defined by optical imaging of intrinsic signals. Neuroimage 11 302-312,... 

Tommerdahl M, Favorov O, Whitsel BL. 2002. Optical imaging of intrinsic signals in somatosensory cortex. Behav Brain Res 135 83-91. 

Boenhoffer, T. A., G. Optical imaging based on intrinsic signals. The methodology. Brain Mapping the methods Academic Press London, 1996 Vol. pp 55-97. 

Timecourse of optical signal, (a) A series of images showing the temporal development of intrinsic cortical response (indentation of D2, pentothal anesthesia). Each frame 200ms. BV, blood vessel map. Scale bar 1 mm. (b) Magnitude of reflectance change (in box at BV)... 

Christopher Fang-Yen and Michael S. Feld give an overview on intrinsic optical signals in nerve tissue that can be used for functional neural imaging and discuss various spectroscopic techniques for their measurement. 

Tsytsarev, V. Premachandra, K. Takeshita, D. Bahar, S. Imaging cortical electrical stimulation in vivo, fast intrinsic optical signal versus voltage-sensitive dyes. Opt. Lett. 2008, 33, 1032-1034. 

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