Intrinsic component

These studies of protein-bound heterometallic cubanes have amply demonstrated that the heterometal site is redox active and able to bind small molecules. Although they have yet to be identified as intrinsic components of any protein or enzyme (except as part of the nitrogenase FeMo cofactor cluster (254)), they are clearly attractive candidates for the active sites of redox enzymes. 

Purines — These molecules have basic skeletons of purine heterocycles. Adenine and guanine, intrinsic components of nucleic acids, are also ubiquitous molecules. Related molecules are isoguanine, xanthine, and uric acid. 

Not all faeces were avoided no species significantly avoided the herbivore faeces tested (whiptail wallaby) or the reptilian predator. Their avoidance of mammalian predator faeces, however, suggests that there may be an intrinsic component to such faeces that elicits a response. The novel odour (acetic acid) was never avoided by M. cervinipes and U. caudimaculatus however, R.fuscipes avoided this odour twice, its most consistent avoidance response, which I am at a loss to explain. Quoll faeces (familiar marsupial predator) were avoided on 75% of sampling occasions, the... 

Numerous definitions and criteria of quality have been published (JL, jD and in some areas, e.g. Florida, wide ranging guidelines have been adopted and laws enacted for the sole purpose of maintaining quality levels. Extensive advances have been made in quality control or quality assurance programs (8) yet many difficult and complex problems remain as intrinsic components of the industry. Thus as the impetus for quality improvement has evolved, it has become a widely recognized fact that certain technological advances were required before qualitative progress could be realized. 

The physiological roles of these metals have not been identified. Thus, the possibility exists that these metals are copurified contaminants. Table I indicates the amounts of metals insensitive to repeated crystallization this provides strong evidence that they are intrinsic components. This is the case for the amount of copper (3 Cu/enzyme), which is consistent with the X-ray structure as described below. 

It has long been proposed that cytochrome c oxidase contains various phospholipids as intrinsic constituents and that two or three cardiolipins are essential for its catalytic activity (Robinson et al., 1980 Robinson, 1982 Sedlak and Robinson, 1999). However, the composition and structures of phospholipids in the enzyme are still matters of controversy. No experimental evidence has been obtained to discount the proposal that all phospholipids suggested are not intrinsic components of the enzyme. Thus, a careful phospholipid analysis of the crystalline enzyme and an X-ray structure determination are indispensable for the determination of the phospholipid composition. 

The field was 3.0 x 105 V/cm. The results show that W increases with increasing dipole moment of the polymer. Figure 33 shows the room temperature field dependencies of the mobility while Fig. 34 shows the temperature dependencies for a field of 3.0 x 105 V/cm. For TAPC doped PS-1, PS-2, and PS-3, a = 0.069, 0.077, and 0.087 eV, increasing with increasing dipole moment. The values of p0 were 1.5 x 10-2 cm2/Vs for all polymers. The positional disorder parameter was also independent of the polymer. The authors argued that the width of the DOS was determined by an intrinsic component due to the TAPC and an extrinsic component due to the polymer. 

Recently, a sodium ion has been detected in the X-ray structures of the fully oxidized and reduced forms of bovine heart cytochrome c oxidase at 2.3 and 2.35 resolutions, respectively (Yoshikawa et al., 1998). In the bacterial enzyme, a site corresponding to the Na site in the bovine enzyme is occupied by a Ca + ion (Ostermeier et al., 1997). A comparison of the coordination geometry for the bacterial versus the mammalian species shows slight differences, and this observation is consistent with differences in coordination chemistry associated with each of the two metals. Prior to the determination of the X-ray structures, the existence of these metal sites had never been proposed. The presence of these metals in X-ray structure strongly indicates that the metals are intrinsic components of the enzyme. However, as in the case of the Mg and Zn ions, the physiological functions of Na and Ca are not understood. 

The overall residual stress in the film is equal to the sum of the thermoelastic component and intrinsic component. In the case of low deposition temperatures, the intrinsic stress is still the main contributing factor to the overall residual stress. In contrast, in the case of high deposition temperatures, the thermoelastic stress predominates. Therefore, while the signs of these stresses are identical, there is an intermediate deposition temperature for which the residual stress is minimised (Figure 2). 

We have in mind such discoveries as relativity, with its non-Euclidean topology, and quantum theory, with its notion of the discontinuous nature of matter and energy. Yet, in the face of these novel orders of pattern, whose explication was spearheaded by scientific methodology itself, other areas of science, not concerned directly with investigating such areas, have continued to carry the burden of outmoded, false conceptions as intrinsic components of their epistemological equipment. 

Additional polypeptides ascribed to the Cyt b-f complex are a bound form of ferredoxin-NADP reductase (FNR) [99] and one or more smaller polypeptides [100]. An association of the complex with ferredoxin-NADP reductase may be expected in view of the reported role of FNR in cyclic electron flow from PS I to the Cyt complex [101]. FNR remains associated with the complex during the early stages of the purification of the complex but there is no evidence that it is an intrinsic component of the complex necessary for plastoquinol-plastocyanin oxido-reductase. The presence of small polypeptides in the complex requires further investigation. Polypeptides of about 5 kDa have been reported to be associated with the spinach complex [100]. 

The high sensitivity of radiotracer techniques makes these very attractive for determination of diffusion coefficients. Self-diffusion (i.e. diffusion of the intrinsic components of the substance) is of special interest and can only be measured by indicator methods. 

Wu K, Xu JL, Suen PC, Levine E, Huang YY, Mount HT, Lin SY, Black IB (1996) Funchonal trkB neurotrophin receptors are intrinsic components of hie adult brain postsynaphc density. Bram Res Mol Brain Res 43 286-290. 

This technique were used because of its simplicity and its ability to qualitatively decompose the energy at rupture into its two intrinsic components energy for creating new surfaces (essential work of fracture. We) and "plastic" work, or more seemingly dissipated energy due to the deformation of the bulk. 

Additional measurements of the coefficients of iron binding by dietary fibers from various sources are needed, particularly because the published coefficients are based on single samples of wheat and maize brans. The need is made greater by the finding of Thompson et al (65) that method of fiber preparation affected ion exchange capacity for copper and zinc. It would be helpful to learn if iron is similarly affected. Further studies of the importance of the protein that appears to be an intrinsic component of some dietary fibers in binding of iron and other cations are needed. The extent of binding of ferric iron by dietary fibers needs to be evaluated. 

Nota bene, not 12.91/ 2, since the between-assay SD contains an intrinsic component of variation, SDi, which is the lower limit and equals... 

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