Nausea intravenous immunoglobulin

The most frequent adverse effects of intravenous immunoglobulin (Sandoz) for the treatment of various disorders (affecting 1-3% of patients in aU) were headache, nausea, vomiting, and fever. Some other mild sjmp-toms have an incidence below 1%, including abdominal pain, diarrhea, fatigue, malaise, dizziness, myalgia, and chest tightness. 

Mild adverse effects of intravenous immunoglobulin, such as headache, chills, nausea, backache, and flushing, occur at a rate of 5-10% (101,135). Most of these... 

Gastrointestinal Nausea [39, 52 ], vomiting, and diarrhea have been associated with intravenous immunoglobulin [39 ]. 

The most commonly reported adverse events are mild local injection reactions, such as erythema, edema, swelling, pruritus, and local heat [48 , 60, 63 ], whose incidence decreases over time [48 ]. The incidence of non-infusion-site reactions after subcutaneous administration (0.24 events per infusion) is similar to the total incidence of 0.25 events per infusion during treatment with intravenous immunoglobulin [48 ]. Non-infusion-site adverse events after subcutaneous administration include headache, diarrhea, fatigue, and nausea [48 "]. 

Gastrointestinal Gastrointestinal adverse events include nausea, vomiting, anorexia, diarrhea, and cramping [I , SS , 54", 55 , 57 ]. Necrotizing enterocolitis after phototherapy and intravenous immunoglobulin for hemolytic disease of the newborn has been reported in three cases [64 ]. 

Children In 38 children with juvenile derma-tomyositis the rate of adverse events, particularly fever, fatigue, nausea, and vomiting, was higher with intravenous immunoglobulin containing more than 15 pg/ml of IgA [59 ]. Children may be more sensitive to immunological triggers than adults [59 ]. 

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