International Society for Heart and Lung Transplantation

Hosenpud JD, Bennett LE, Keck BM, Boucek MM, Novick RJ. The registry of the international society for heart and lung transplantation seventeenth official report 2000. J Heart Lung Transplan. 2000 19 909-931. 

Currently, MMF is approved for use in kidney, liver, and heart transplants. A recent analysis of 5599 patients in the Joint International Society for Heart and Lung Transplantation (ISHLT) and UNOS Thoracic Registry showed a statistically signihcant survival advantage for MMF compared with azathioprine (1 year, 96% versus 93% 3 years, 91% versus 86%). Efficacy has been demonstrated in combination with both CSA and TAC. 

Winters GL, Marboe CC, Billingham ME. The International Society for Heart and Lung Transplantation grading system for heart transplant biopsy specimens Qarification and commentary. J Heart Limg Transplant 1998 17 754-760. 

Trulock EP, Christie JD, Edwards LB, et al. Registry of the International Society for Heart and Lung Transplantation twenty-fourth official adult lung and heart-lung transplantation report—1007. J Heart Lung Transplant 2007 26(8) 782—95. 

Brann WM, Bennett LE, Keck BM, Hosenpud JD. Morbidity, functional status, and immunosuppressive therapy after heart transplantation an analysis of the joint International Society for Heart and Lung Transplantation/United Network for Organ Sharing Thoracic Registry. J Heart Lung Transplant 1998 17 374-382. 

LT is the best therapeutic option for patients with IPF with life-threatening disease (208-210). Since no medical therapies have been proven to influence survival in IPF, IPF patients should be referred to LT centers at the time of diagnosis (provided no contraindications exist). The decision to list for LT is best made by the local transplant team members, who are familiar with local waiting times. Either single (SLT) or bilateral sequential lung transplantation (BSLT) can be performed (208,209,211). Data from the International Society for Heart and Lung Transplantation (ISHLT) Registry reported that 19% of >17,000 LTs... 

While the number of medical centers performing cardiac transplantation continues to grow, the shortage of donor hearts continues to limit the availability of this type of surgery particularly in the US, where only 2000-2700 procedures a year are performed (Massad 2004 Poston and Griffith 2004 Winkel et al. 1999). Worldwide, an estimated 4000 cardiac transplantations are performed annually (Taylor et al. 2004). As of May 2004,66,000 heart transplantations have been reported to the International Society for Heart and Lung Transplantation (Hosenpud et al. 1999 Taylor et al. 2004). 

Stehlik, J., Edwards, L. B., Kucheryavaya, A. Y. et al. 2010. The Registry of the International Society for Heart and Lung Transplantation Twenty-seventh official adult heart transplant report—2010. / Heart Lung Transplant 29 1089-103. 

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