Intermolecular Tin

Initial Intermolecular Tin-free Animations of Aryl Halides 372... 

Examples of supramolecular association as a result of intermolecular organolead-sulphur interactions are rare and compounds such as Me3PbSMe and Pl PbSPh are monomeric in the solid state463. In contrast, triphenyllead pyridine-4-thiolate, d-Pl PbSCsFLjN464, is a chain polymer as a result of intermolecular N—Pb interactions. The cyclic dithiolate 2,2-diphenyl-l,3,2-dithiaplumbolane 177465 self-assembles in the solid state via intermolecular tin-sulphur interactions into a one-dimensional polymeric array. The intramolecular Pb—S bond lengths amount to 2.52(2) and 2.49(1) A and the intermolecular Pb—S distances are 3.55(2) A. 

Initial Intermolecular Tin-Free Aminations of Aryl Halides... 

Intermolecular Tin... 7r-Aryl Interactions fact or artifact A New Bonding Motif For Supramolecular Self-Assembly in Organotin Compounds... 

Compounds containing at least one tin-oxygen bond in a saturated five-membered ring have a tendency to self-assemble by intermolecular tin-oxygen bonding. Such compounds include dioxastannolannes (a class of antitumor-active compounds)... 

The second set of examples involves the use of thionium ions as electrophiles in inter- and intramolecular processes to obtain a-substituted sulfides (see 24 25, Scheme 20.7T which is the most common type of Pummerer reaction. Applications of this classical Pummerer rearrangement are exemplified in the synthesis of trans-solamin, the synthesis of indolizidine alkaloids, and the synthesis of the CDE ring of erinacine E. The first exanple fScheme 20.10 uses Pummerer chemistry in the generation of a thionium ion, which reacts in an intermolecular tin-mediated ene reaction the second one fScheme 20.11 uses Pummerer chemistry to introduce a nitrogen-containing heterocycle by intramolecular addition to form the coniceine core and the third example fScheme 20.12 is an intramolecular silicon-induced Pummerer reaction with oxygenated nucleophiles applied to the synthesis of a precursor of erinacine. Details of these Pummerer-based strategies are discussed below. 

These tin(II) ring compounds are crystalline with remarkable thermal stability. They may be polymeric in the solid state with intermolecular tin-oxygen bridges, but in pyridine... 

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