Interface membrane-inspired

The tracheo-bronchial epithelium forms the interface between the conducting airways and inspired air. As described above, the epithelium is layered upon a connective tissue substratum consisting of a basement membrane, lamina propria, and submucosa [6], The submucosa contains elastic fibres, a muscularis mucosa, connective tissues and seromucous glands. Lymphatics are also located in the bronchial walls [2],... 

In contrast to polymersomes, there are various models of planar membranes monolayers at the water-air interface, free-standing bilayers, and solid-supported membranes. The functionality of proteins in natural membranes strongly depends on their mobility in the matrix, and this is thus an essential prerequisite for artificial membranes to mimic the dynamic environment of biomembranes in order to serve as templates for biomolecules.Therefore, the building blocks forming a bio-inspired membrane need to possess high flexibility to compensate the hydrophobic mismatch between the size of the biomolecules, and the membrane thickness. Furthermore, a variety of membrane properties (thickness, polarity, and surface charge) have to be considered for the successful insertion/attach-ment of biomolecules. Decoration of polymer membranes with biomolecules, either on their surfaces or inside the bilayers, can be achieved by various approaches, such as physical adsorption, insertion, and covalent binding. Compared to physical immobilization of biomolecules on... 

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