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Interactions, analyte-ligand

Chiral Chromatography. Chiral chromatography is used for the analysis of enantiomers, most useful for separations of pharmaceuticals and biochemical compounds (see Biopolymers, analytical techniques). There are several types of chiral stationary phases those that use attractive interactions, metal ligands, inclusion complexes, and protein complexes. The separation of optical isomers has important ramifications, especially in biochemistry and pharmaceutical chemistry, where one form of a compound may be bioactive and the other inactive, inhibitory, or toxic. [Pg.110]

Udenfriend, S., Gerber, L. Nelson, N. (1987) Scintillation proximity assay - a sensitive and continuous isotopic method for monitoring ligand receptor and antigen-antibody interactions. Analytical Biochemistry 161,494-500. [Pg.70]


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