Instrumentation principles

Instrumentation. Principle of Mass Spectrometry. Characteristics and Interpretation of Molecular Mass Spectra. Applications of Mass Spectrometry. 

Figure 7.5 Time-correlated single-photon counting instrument principle. Courtesy of Jobin Yvon.

Fluorescence methods are inherently capable of detecting much lower concentrations of analytes, because of the instrumental principles involved. Consider, for example, a comparison of the light intensities measured in blank solutions by... 

Application of some of the instrumentation principles of HPLC to electrophoresis, bearing in mind the need to cause all of the components of a mixture to migrate differently, has led to the development of several related techniques that are particularly useful in the amino-acid and peptide fields (Baker, 1995). A typical electro-pherogram (Figure 4.16) indicates the salient features of the capillary zone electrophoresis (CZE) analysis protocol. 

Instrument Principle Unit of analysis Sample state Data Cost of analysis Applications... 

Instrumentation. Principle of mass spectrometry. Characteristics and interpretation of molecular mass spectra. Applications of mass spcciro-. metry. 

Morris AS (2001) Measurement instrumentation principles. Butterworth-Heinemann, Woburn Santochi M, Dini G (1998) Sensor technology in assembly systems. Ann CIRP 47(2) 503-524 Soloman S (2010) Sensors handbook, 2nd edn. McGraw-Hill, New York... 

Figure 2 Comparative overview on different instrumentation principles used in molecular absorption spectrometry.

Fluorescence spectroscopy has been widely applied in analytical chemistry. It is a sensitive technique that can detect very low concentrations of analyte because of the instrumental principles involved. At low analyte concentrations, fluorescence emission intensity is directly proportional to the concentration. Fluorescent materials and green fluorescent protein have been extensively used in the construction of the fluorescent biosensor. 

Tong, H.-M. and L. T. Nguyen (eds.), New Characterization Techniques for Thin Polymer Films , Wiley-Interscience, New York, 1990. This book provides a description of the instrumentation, principle of operation, areas of application and data analysis methods of the new techniques. 

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