Postsynthetic modification inorganic

Furthermore, the postsynthetic modification of MOFs, either at the organic linkers or at the inorganic clusters [77, 136-139], is the best tool to open new possibilities to design efficient confined catalytic systems having defined single active site and fiexibility to accommodate substrates in a specific orientation in one word, the fine tuning of MOFs allows enzyme mimicking. 

There are several basic approaches to the design of heterogeneous catalysts based on MOFs the use of MOFs as classical supports for an active metal, the immobilization of a catalytically active site in the framework per se (in the inorganic node or in the organic linker), host-guest interaction, postsynthetic modification of the framework, and so forth. These approaches will be discussed later in more detail. 

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