Inherited cores

FIGURE 31.10 Backscattered electron image of zircon grain 4 showing an inherited core (dark area 1755 12 Ma) and a younger rim (lighter area). 

Apparently, this is due to some memory effect the core, which existed in the parent globular conformation (Fig. lb), was simply reproduced upon refolding caused by the attraction between H units. One may say that the features of the parent conformation are inherited by the protein-like copolymer. Looking at the conformations of Fig. 3, it is natural to argue that proteinlike copolymer globules could be soluble in water and thus they are open to... 

For copolymers with some protein-like comonomer distributions, individual copolymer chains can memorize or inherit its parent globular state namely, their folding back into the core-shell nanostructure is much easier, resulting in a smaller and denser single-chain particle in comparison with their counterparts, randomly distributed comonomers on the... 

The molecular basis of inherited defects is established for a number of diseases and altered glycosylation patterns have been observed to be associated with these. For example, IgG Fc fragment conserved site glycans lacking in outer arm Gal residues increase in rheumatoid arthritis, tuberculosis and Crohn s disease. There is also an Fab-specific increase in glycans bearing a bisecting Gn and a core Fuc [148]. 

Known DNA repair-deficient syndromes mainly affect the nucleotide excision repair pathway and the mechanisms for strand break repair. No human disorders caused by inherited BER deficiencies have been identified. The most hkely explanations are based on the generated mice knock out models. Deficiency of a single glycosylase may not cause an overt phenotype as the substrates can be repaired by other glycosylases or by other repair systems. In contrast, knock out of BER core proteins often induces embryonic lethahty. 

A result which sheds light on the properties of a Tucker3 model is the following. Suppose that a (P, Q, R) Tucker3 models fits exactly a three-way array X of rank S. Then the core-array G of the Tucker3 model also has rank S. Hence, the rank of the three-way array G inherits the rank of X [Carroll et al. 1980],... 

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