Infrared multi-photon dissociation, IRMPD

In all three instrumental configurations, it is possible to induce decomposition of the ion trapped inside the ICR cell not only by collisional experiments, but also by interaction with slow electrons (electron capture dissociation, ECD) or by irradiation with an infrared (IR) laser beam (infrared multi photon dissociations, IRMPD). Experiments of this type (mainly devoted to polypeptide identification) allow to maintain the high-vacuum conditions inside the ICR cell, which are necessary to achieve the high-resolution conditions. 

M. C. Crowe and J. S. Brodbelt, Infrared multi-photon dissociation (IRMPD) and collisionally activated dissociation of peptides in a quadrupole ion trap (QIT) with selective IRMPD of phosphopeptides, J. Am. Soc. Mass Spectrom. 15, 1581-1592, (2004). 

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