Influenza viruses, vaccines and

The manufacturers advise that antivirals active against influenza such as oseltamivir and rimantadine should not be given until 2 weeks after the administration of live influenza virus vaccines, and that these vaccines should not be given until 48 hours after stopping the antiviraL This is because of the theoretical concern that these antiviral drugs will inhibit replication of live vaccine virus, and therefore reduce its effect. Note that most influenza vaccines are inactivated (split virion or surface antigen), and that these would not be expected to be affected by antivirals active against influenza. 

Bachmayer H. 1976. SpKt and subunit vaccines. In P. Selby (Ed.), Influenza Virus, Vaccines, and Strategy, p. 149. New York, Academic Press. 

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