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Influence of Isomerism on Developmental Toxicity Thalidomide

Exposure to certain xenobiotics is associated with adverse endocrine effects. These chemicals are commonly referred to as endocrine disrupting chemicals. Endocrine disruption can interfere at all levels of physiological organization and with all endocrine organs, for example mimicking natural hormones, blocking endogenous receptors, or directly affect the system itself. [Pg.147]

Developmental toxicology is the study of adverse effects in a developing organism. Teratology is a sub-discipline of developmental toxicology that focuses on the specific time period between conception and birth. Many teratological effects are quite obvious, for example, cleft palate and missing [Pg.147]


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