Inflammatory bowel disease mucosal damage

EP4 receptor agonists have drawn much attention to the effects of promoting osteogenesis [61] or suppressing colitis and mucosal damage [62], because the potential of an EP4 receptor agonist for treatment in bone diseases or inflammatory bowel disease has been examined in clinical trial [61],... 

Intrinsic diseases of the small intestinal mucosa may impair mineral absorption. Such conditions as celiac sprue, dermatitis herpetiformis, infiltrative lymphomas, and occasionally inflammatory bowel disease produce diffuse mucosal damage. Protein energy malnutrition causes similar damage, and tropical enteropathy affects part of the population of developing countries living under adverse nutritional and hygienic conditions. 

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