Inferior olive olivocerebellar projection

Fig. 172. Origin from the border region of the rostral and caudal medial accessory olive of the olivocerebellar projection to the electrophysiologically identified x zone in the cat, a = a zone b = b zone P = subnucleus beta cpCj = CpC, zones coll = inferior colliculus d, dj = d, and d2 zones dmcc = dorsomedial cell column MAO = medial accessory olive ml = midline pvg = lateral border of vermis x = x zone IV, V = lobules IV and V. Redrawn from Campbell and Armstrong (1985).

Fig. 185. The olivocerebellar projection to the pyramis and the uvula (lobules 8 and 9) of tbe rat cerebellum. A,B- Olivocerebellar projection zones of the lobules 8 and 9. C. Origin of these projections, indicated in diagrams of transverse sections through the inferior olive, a = subnucleus a of the medial accessory olive b = subnucleus b of the medial accessory olive beta = group beta c = subnucleus c of the medial accessory olive d = dorsal accessory olive dm = dorsomedial subnucleus m = medial accessory olive pr = principal olive 8 and 0 = lobules VIII and IX of Larsell. Relabelled and reproduced from Eisenman (1984).

Fig. 187. Olivocerebellar projection to the uvula based upon retrograde tracing experiments in the cat (Kanda et al. 1989). The bottom diagrams of the flattened inferior olive were reconstructed from their data, beta = subnucleus beta cMAO = caudal medial accessory olive dc = dorsal cap dlPO = dorsal leaf of the principal olive dmcc = dorsomedial cell column DU = dorsal folia uvula rMAO = rostral medial accessory olive vlo = ventrolateral outgrowth vlPO = ventral leaf of the prineipal olive VU = ventral folia uvula.

Zonal projections of the inferior olive to the nodulus (lobule X) and the flocculus have been substantiated in different species. Purkinje cells of these lobules are uniformly Zebrin-positive in rat, mouse, opossum, squirrel monkey (see Section 6.1.3.) and rabbit (Jaarsma unpublished observations). A compartmental subdivision of the white matter of the nodulus and the flocculus was demonstrated with AChE-histochemistry in the rabbit and the monkey (Section 6.1.5.) and correlated with the olivocerebellar projection to these lobules (Voogd et al., 1987a,b Tan et al., 1995a,b). 

Wassef M, Chedotal A, Cholley B, Thomasset M, Heizmann CW, Sotelo C (1992a) Development of the olivocerebellar projection in the rat I. Transient biochemical compartmentation of the inferior olive. J. 

Whitworth RH Jr, Haines DE (1986b) The inferior olive of Saimir sciurus olivocerebellar projections to the anterior lobe. Brain Res., 372, 55-72. 

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