Infection carbohydrate-based drugs

Infection. Carbohydrate-based drugs that treat infection include antibiotics and anti viraMn this section are agents to treat sepsis and those that act as vaccines. Also, no attempt is made to cover all carbohydrate-based anti-infectives because of the number involved and because antibiotics are covered more thoroughly elsewhere (10). 

Indeed, two orally delivered, carbohydrate-based, silica-linked, gastrointestinal anti-infective therapies were advanced to clinical trials. Synsorb Pk was developed for the treatment of E. coli infections to prevent hemolytic uremic syndrome. The target E. coli variant produces verotoxin,the toxin in "hamburger disease." The other silica-linked oligosaccharide drug, Synsorb Cd, was for the treatment of C. difficile-associated diarrhea. Both compounds were discontinued in development. 

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