Induction in Liver and Intestine

1 MDR1 (ABCB1 )IP-f p. Pew studies addressed the induction of rat Mdrl genes on the mRNA level, only where the two rodent orthologs of human MDR1 can be differentiated. Rats, which were treated with PCN, spironolactone, ordexamethasone, did not show any induction of Mdrl a or Mdrl b in liver or intestine. In contrast, DAS [Pg.117]

Transporter Species Inducer0 Tissuc/Ccll Effect NRC Reference [Pg.118]

Transporter Species Inducer Tissue/Cell4 Effect NRC Reference [Pg.119]

MRP2 Human Rifampin HepG2 (1) mRNA, protein PXR [101, 106] [Pg.119]

Transporter Species Inducer11 Tissue/Cell6 Effect NRC Reference [Pg.120]

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