In Vitro Safety Pharmacology Profiling an Important Tool to Decrease Attrition

In Vitro Safety Pharmacology Profiling an Important Tool to Decrease Attrition 

Hit and Lead ProJUir. Edited by Bernard Faller and Laszlo Urban Copyright 2009 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 978-3-527-32331-9 

We do not address early toxicology profiling in this section, that is, those phenotypic assays for which molecular targets are hardly known and which attempt to be predictive of the standard later stage assays, such as those covering genotoxicity, hepatotoxicity or phototoxicity. These are all covered elsewhere in this book. 

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