In vitro ciliary activity, cigarette smoke fractions, and dose level

In vitro Ciliary Activity, Cigarette Smoke Fractions, and Dose Level 

Smoke Fraction From Which Aqueous Extract was Obtained % of Smoke Immediate Complete Ciliastasis at Dc Complete Ciliastasis in 10-40 min at DIO No Apparent Ciliastasis at Do Dc/Do 

Number in parentheses is percentage of smoke fraction that is soluble in water. 

Dose reduction (effectively, dilution) of MSS or some of its ciliastatic components or ciliastatic fractions eventually results in a dose or concentration level at which no ciliastasis is produced in the in vitro systems used. 

Ciliastatic compounds inhaled nasally are removed from the inhaled gas stream by resorption.  

---