In combo

Avdeef A, Tsinman O (2006) PAMPA—a drug absorption in vitro model 13. Chemical selectivity due to membrane hydrogen bonding In combo comparisons of HDM-, DOPC-, and DS-PAMPA models. Eur J Pharm Sci 28 43-50. 

Aprepitant (Emend) [Centrally Acting Antiemetic] Uses Pre-vents N/V assoc w/ emetogenic CA chemo (eg, cisplatin) (use in combo w/ other antiemetics) Action Substance P/neurokinin l(NKi) receptor antagonist Dose 125 mg PO day 1, 1 h before chemo, then 80 mg PO qAM days 2 3 Caution [B, /-] Contra Use w/ pimozide, Disp Caps SE Fatigue, asthenia, hiccups Interactions T Effects W/ clarithromycin, diltiazem, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, troleandomycin T effects OF alprazolam, astem-izole, cisapride, dexamethasone, methylprednisolone, midazolam, pimozide, terfe-nadine, triazolam, chemo agents, eg, docetaxel, etoposide, ifosfamide, imatinib, irinotecan, paclitaxel, vinblastine, vincristine, vinorelbine i effects W/ paroxetine,... 

Esomeprazole (Nexium) [Gastric Acid Inhibitor/Proton Pump Inhibitor] Uses Short-term (4-8 wk) for erosive esophagitis/GERD H. pylori Infxn in combo w/ antibiotics Action Proton pump inhibitor, gastric acid Dose Adults. GERD/erosive gastritis 20 0 mg/d PO x 4-8 wk 20 0 mg IV 10-30 min inf or >3 min IV push, 10 d max Maint 20 mg/d... 

WARNING Excessive doses alone or in combo w/ other CNS depressants can be cause of death use w/ caution in depressed or suicidal pts Uses Mild-mod pain Action Narcotic analgesic Dose 1-2 PO q4h PRN in hepatic impair, elderly... 

Carbohydrates have many useful functions. They are used for the storage and generation of energy they are important structural components, both intra- and extracellar and they may be iiansfonned into other, totally different kinds of molecules, like amino acids, lipids, and nucleic acids. When carbohydrates attach to proteins and lipids, they form glycoproteins and glycolipids. The latter complex molecules may be found in Combo Circle and will be seen at show time. 

Lipids can combine with carbohydrates or proteins to form glycolipids and lipoproteins. These will be examined in greater detail in Combo Circle. 

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