In an incompatible world

Smith, D.H. Information Integration in an Incompatible World . In Chemical Structure Information Systems, W.A. Warr, Ed. ACS S5onposium Series 400, American Chemical Society Washington, 1989, pp. 18-40. 

In an ideal world all chemical reactions would be carried out in water because solvent is the main by-product of all chemical processes and is difficult to recycle. For many reactions water as solvent is virtually impossible as reagents and/or catalysts are incompatible and/or insoluble in water. But Diels-Alder reactions are faster and more stereoselective in water even though the reagents generally don t dissolve.11 So cyclopentadiene 24 adds to methyl acrylate 59 with poor endo selectivity in cyclopentadiene as solvent. The selectivity improves in ethanol but is... 

If a testing facility is too small to handle the volume of work it has set out to do, there may be an inclination to mix incompatible functions. Examples might include the simultaneous conduct of studies with incompatible species (e.g., old world primates and new world primates) in the same room, setting up a small office in the corner of an animal housing area, housing an excessive number of animals in a room, or storing article/carrier mixtures in an animal room. 

Another long-standing issue in the world of fall protection is the issue of incompatible connections or roll-out (also known as forced rollout) of snap hooks and carabiners. Many accidents were found to be the result of an incompatible connection that put a substantial load on the gate of a snap hook or carabiner and, as a result, failed the connection. The Z359 committee opted to increase the gate-face strength on carabiners and snap hooks from 220 lbs to 3600 lbs and the side-load strength from 350 lbs to 3600 lbs to combat incompatible connections. The A 10.32 standard still... 

The online coupling of a separation device with mass spectrometry is an analytical approach that can help in the analysis of real-world samples such as environmental samples and biological tissues and fluids. This online marriage between two stand-alone analytical techniques can provide an unequivocal characterization of individual components of such complex samples and greatly increases the information content of those components. Several issues that must be addressed to achieve an ideal combination. A major concern is the pressure mismatch. The solvent incompatibility also becomes an issue in the coupling of LC and CE with mass spectrometry. Thus, online coupling requires an interface that can transport the separated components into the ion source without affecting their resolution or the performance of a mass spectrometer. Not all types of mass spectrometers... 

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