Implied Proximity Operator

The effect of proximal groups on the diastereoselectivity in the addition of allylindium to a carbonyl group has been extensively surveyed.153 When a- and /3-hydroxy aldehydes are subjected to the allylation, excellent diastereocontrol is realized, syn- 1,2-Diol and anti- 1,3-diol products are formed, respectively, at accelerated rates (Tables 1 and 2). Protection of the free hydroxy group results in the alternative formation of 1,2-anti products. High stereoselectivities have been observed for indium-promoted allylations of a- and /3-hydroxy aldehydes in aqueous media, implying that a chelate control still operates even in water.72,73,154-158... 

Surgical applications seem to be the worst-case scenario for the use of robots. Not only the task, by definition, implies close proximity to a human being where the actions of the robot are meant to have a consequence, but also the patient has no opportunity to perceive and, thus, react to robot actions. Furthermore, safety is a real and very important concern for surgery. Potential risks associated with any new technology to be used in operating rooms are meticulously evaluated before its approval. 

---