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Immunosuppression, gastrointestinal immune

Gusperimus is a guanidine derivative with antitumor and immunosuppressive properties. Its mechanism of action is not well understood and may involve blockade of the maturation of B and T lymphocytes and monocytes, with inhibition of both cell-mediated and antibody-mediated immunity. In preliminary clinical trials in transplant patients, adverse effects at low doses included mild-to-moderate leukopenia, facial and perioral numbness, anorexia, gastrointestinal disturbances, facial flushing. [Pg.1564]

See other pages where Immunosuppression, gastrointestinal immune is mentioned: [Pg.1217]    [Pg.678]    [Pg.1373]    [Pg.384]    [Pg.82]    [Pg.580]    [Pg.36]    [Pg.63]    [Pg.447]    [Pg.1276]    [Pg.957]    [Pg.326]    [Pg.331]    [Pg.87]    [Pg.122]    [Pg.898]    [Pg.8]    [Pg.129]    [Pg.966]    [Pg.184]   


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Gastrointestinal immunity

Immunosuppressant

Immunosuppression

Immunosuppressives

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