Immunosensors dimensions

Figure 2 shows the most abundant class of antibodies found in blood serum and lymph - immunoglobulin G (IgG). IgG of molecular mass about 156 000, is most frequently used as a receptor in immunosensors. According to X-ray data6 8, IgG is a Y-shaped molecule consisting of two identical antigen binding Fab arms of dimensions 6.5 nm by 3.5 nm and an inactive Fc shank of dimensions 5 nm by 3.5 nm. 

Another portable SPR immunosensor designed for on-site determination of low-molecular-weight compotmds by immunosensing was developed with the dimensions of 16 cm X 9 cm x 6 cm with four sensing microchannels. Highly sensitive and selective analysis of benzo[a]pyrene and 2-hydroxybiphenyl was realized by using an indirect competitive immunoreaction based on SPR detection. The sensitivity of the compact, portable SPR sensor to ppb levels of the two compounds was equivalent to that obtained with a conventional SPR apparatus. ... 

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