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Immunogenicity of Free and Conjugated Drugs

BA Pham NH. Structure-activity studies on drug-induced anaphylactic reactions. Chem Res Toxicol 1994 7 703. Reproduced with permission from American Chemical Society [Pg.39]

2 Mediator Release by Free and Conjugated Drugs in Immediate Allergic Reactions [Pg.40]

In allergic subjects, IgE antibodies, as well as being free in serum, are fixed to the exfiacellular D1 distil and D2 proximal domains of the FceRl receptor on mast cells and basophils via the Ce2 and Ce3 domains of the antibody Fc region. [Pg.40]

See other pages where Immunogenicity of Free and Conjugated Drugs is mentioned: [Pg.38]   


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