Immunocompromised patient infection Solid-organ transplantation

Concerns have been raised about the use of adjuvanted pandemic vaccines in patients with immune disorders, such as immunodeficiency, autoimmune disorders, and solid organ transplants. To date, postmarketing surveillance has not found evidence for causality of any adverse reactions in such patients. Viral infections, such as influenza, can lead to severe complications in immunocompromised patients. 

Infections play an important role in solid organ transplantations. Besides the usual pathogenic organisms, immunocompromised patients are susceptible to infections with organisms that are normally not pathogenic or only sometimes pathogenic. 

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