Immune-regulatory properties

Becher B, Bechmann 1, Greter M (2006) Antigen presentation in autoimmunity and CNS inflammation how T lymphocytes recognize the brain. J Mol Med 84 532-543 Becher B, Prat A, Antel JP (2000) Brain-immune connection Immune-regulatory properties of CNS-resident cells. GLIA 29 293-304... 

Tsuji and co-workers reported the perfluoroalkylation of bromo-thiophenes to produce a compound that was found to have excellent anti-inflammatory and immune-regulatory properties. The reaction yielded only a small quantity of the desired product (-15%), with the reduced (-H) compound (not shown) being the major by-product. 

Axel R (2005). Scents and sensibility A molecular logic of olfactory perception (Nobel lectui e). Angew Chem Int Ed Engl 44 6110-6127. Becher B, Prat A, An tel JP (2000). Brain-immune connection Immuno-regulatory properties of CNS-resident cells. Glia 29 293—304. 

Becher B, Prat A, Antel JP (2000) Brain-immune connection Immuno-regulatory properties of CNS-resident cells. Glia 29 293-304. 

Williams K, Ulvestad E, Antel J (1994) Immune regulatory and effector properties of human adult microglia studies in vitro and in situ. Adv Neuroimmunol 4 273-281. 

Khan S, Malik F, Suri KA, Singh J (2009) Molecular insight into the immune up-regulatory properties of the leaf extract of ashwagandha and identification of Th- 1 immunostimulatory chemical entity. Vaccine 27 6080-6087... 

The Th-1 /Th-2 paradigma forms a core mechanism regulating the nature of an immune response. More recently, this concept was further developed by identifying Th-subsets with predominantly suppressing properties, T-regulatory cells (Treg). These cells also play a major role in keeping those cells at rest, which have escaped central tolerance (peripheral self tolerance). 

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