Immune globulin for IV use

Kawasaki disease Immune globulin (IV)2 400 mg/kg IV daily for 4 consecutive days within 4 days after the onset of illness. A single dose of 2 g/kg IV over 10 hours is also effective. Effective in the prevention of coronary aneurysms. For use in patients who meet strict criteria for Kawasaki disease. 

Idiopathic thrombocytopenic purpura (ITP) Immune globulin (IV)2 Consult the manufacturer s dosing recommendations for the specific product being used. Response in children with ITP is greater than in adults. Corticosteroids are the treatment of choice in adults, except for severe pregnancy-associated ITP. 

Lymphocyte immune globulin, an immunoglobulin with inununosuppressive properties (15 mg/kg/day IV for 14 days), is used in the prevention or treatment of acute renal allograft rejection, in aplastic anemia, skin allotransplantation, and in bone marrow allotransplantation (see also Figure 28). 

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