Imaging bone metastases with

Figure 18.6 Kinetics of F-choUne. After transport into cells, choline is phosphory-lated by choline kinase, and via intermediate steps, to phosphatidylcholine, a ubiquitous component of cell membrane lipids. Inserted image on the right demonstrates high physiologic hepatic tracer retention (arrow). FocaUy increased activity in the region of the bladder (arrow) is consistent with primary bladder carcinoma, since physiologic urine activity appears later during imaging. The focus of increased activity in the right lower pelvis corresponds to a bone metastasis (arrow).

Fig. 12.4a-f. Orbital metastasis of prostate cancer affects major wing of sphenoid bone and extraconal compartment of orbit, with bony spiculae extending into the intra-oibital soft tissue mass (arrows). Metastasis causes proptosis of left eyeball (axial MDCT images, a and b), compression of optic nerve in... 

Indications for image-guided percutaneous bone biopsy are bone metastases and primary bone tumors. The biopsy is performed to verify that a suspicious bone lesion is indeed a metastasis, or in order to detect the primary tumor. In patients with breast cancer, hormone sensitivity of a metastatic bone lesion can be important for adequate therapy. In suspected primary bone tumors. 

Civardi G, Livraghi T, Colombo P et al (1994) Lytic bone lesions suspected for metastasis ultrasonically guided fine-needle aspiration biopsy. J Clin Ultrasound 22 307-311 Comfort TH,Arafiles RP (1978) Barbotage ofthe shoulder with image-intensified fluoroscopic control of needle placement for calcific tendinitis. Clin Orthop 135 171-178 Connell DA, Ali KE, Ahmad M et al (2006) Ultrasound-guided autologous blood injection for tennis elbow. Skeletal Radiol 35 371-377... 

---