Diagnostic Imaging Applications

DTPA has also been used in the peptide-based " in-DTPA-octreotide. Octreotide is a shortened peptide analog of somatostatin designed to be more stable in vivo. Radiolabeling of octreotide for diagnostic imaging applications with radioisotopes for PET or SPECT has been investigated,... 

As far as applications of XDI, the comparison with MRI is illuminating. MRI has from its beginnings found a ready application for soft-tissue imaging in diagnostic radiology, driven by the powerful market forces at work in the health-care sector. 

Polymersomes offer advantages for clinical therapeutic and diagnostic imaging applications. The ratio of the hydrophilic-to-hydrophobic volume fraction is the key in determining the mesoscopic formulations among micelles (spherical, prolate, or oblate) or vesicles (polymersomes) in aqueous solution [33-35]. In general, a proportion of hydrophilic block-to-total polymer from 25 to 45% favors polymersome formation, while block copolymers that have proportions greater than 45% favors micelle formation [36]. 

Revisions in Chapter 7 are related to the increased interest in lipid analysis, notably boosted by introduction of the new omics field-lipidomics-and by developments of MS imaging as a robust new application of MALDI-MS. In addition, novel potentials of lipid analysis in applications of the direct desorption from solid surfaces and MALDl-MS imaging to diagnostics using Upids as disease markers are described. 

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