Idonic acid preparation

Methods for the preparation of L-idonic acid and L-xylose were discussed in Ref. 1. 

Raney nickel) of the potassium salt of D-xy/o-5-hexulosonic acid oxime produces a mixture of 5-amino-5-deoxy-L-idonic and -D-glu-conic acid in the ratio of 2 1, which is converted into the methyl ester hydrochloride. Upon treatment with alkali, spontaneous cyclization to the pair of 1,5-lactams occurs. 5-Amino-5-deoxy-L-idono-l,5-lactam and 5-amino-5-deoxy-D-glucono-l,5-lactam were separated by recrystallization. The optical rotatory dispersion curves of both compounds were discussed. A new type of lactam, namely, 2-enamino-N,N -bis[(p-methoxycarbonyl)phenyl]-4-(D-gaiacfo-penta-acetoxypentyl)-4-butanelactam was prepared by tbe reaction of 5,6,7,8,9-penta-0-acetyl-3,4-dideoxy-D-ga/ocfo-nonulos- rcns-3-en-l-onic acid with methyl p-aminobenzoate. 

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