Ibuprofen enantioselective membranes

Miyako, E., Maruyama, T., Kamiya, N. and Goto, M. (2003) Enzyme-facilitated enantioselective transport of (S)-ibuprofen through a supported liquid membrane based on ionic liquids. Chemical Communications, 2926. 

Jiao, P. If, Huang, K. L., Peng, X. H., Zhao, X. H., Yu, J. G. (2006). Hollow fiber liquid-supported membrane technology for enantioseparation of racemic salbutamol by combinatorial chiral selectors. J. Central South Univ. Technol., 13, 39-43. Miyako, E., Maruyama, T., Kamiya, N., Goto, M. (2003). Enzyme-facilitated enantioselective transport of (S)-ibuprofen through a supported liquid membrane based on ionic liquids. Chem. Commun., 2926-7. 

Apart from catalysis, supported IL membranes have also been investigated for a variety of separation applications [23], which ranged from the separation of isomeric amines [24] to the enzyme-fadlitated transport of (S)-ibuprofen through a supported liquid membrane [25], The latter study demonstrated the selective separation of the (S)-enantiomer from the racemic mixture (see Figure 3). The concept was that by employing certain enzymes, such as lipase, it would be possible to catalyze the hydrolysis or the esterification ofibuprofen enantioselectively. In this investigation... 

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