Hypophosphatemia clinical presentation

R. Subramanian and R. Khardori Severe hypophosphatemia pathological implications, clinical presentations and treatment. Medicine 79,1 (2000). 

Subramanian R, Khardori R. Severe hypophosphatemia. Pathophysiologic implications, clinical presentation, and treatment. Medicine (Baltimore) 2000 79 1-78. 

III. Clinical presentation. Within minutes to a few hours after ingestion, victims develop profound hypokalemia and skeletal muscle weakness progressing to flaccid paralysis of the limbs and respiratory muscles. Ventricular arrhythmias, hypophosphatemia, rhabdomyolysis, acute renal failure, and coagulopathy may also occur. Gastroenteritis with severe watery diarrhea, mydriasis with impaired visual accommodation, and CNS depression are sometimes present. More often, patients remain conscious even when severely Intoxicated. 

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