Hyphenated Mass Spectrometric Techniques

Trends in mass spectrometry focus on the improvement of instrumentation, of several techniques in order to minimize sample volume, to improve sensitivity and to reduce detection limits. This is combined with increasing the speed of several analyses, with automation of analytical procedures and subsequently reducing the price of analysis. A minimizing of sample volumes means a reduction of waste volume with the aim of developing green chemistry . Furthermore, new analytical techniques involve a development of quantification procedures to improve the accuracy and precision of analytical data. Special attention in future will be given to the development of hyphenated mass spectrometric techniques for speciation analysis and of surface analytical techniques with improved lateral resolution in the nm scale range. 

Maurer, H.H. Hyphenated mass spectrometric techniques - indispensable tools in clinical and forensic toxicology and in doping control. J. Mass Spectrom. 41, 1399-1413 (2006)... 

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