Hypericum perforatum phloroglucinols from

Hypericum perforatum (Clusiaceae), commonly known as SJW, is used in many countries for the treatment of mild-to-moderate forms of depression. Several clinical studies provide evidence that SJW is as effective as conventional synthetic antidepressants (46-51). From a phytochemical point of view, H. perforatum belongs to one of the best-investigated medicinal plants. A series of bioactive compounds have been detected in the crude material, namely phenylpropanes, flavonol derivatives, biflavones, proanthocyani-dins, xanthones, phloroglucinols, some amino acids, naphthodianthrones, and essential oil constituents (Fig. 3) (52-54). 

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