Hypericum perforatum antimicrobial activity

Another common plant that appears to have some activity against MRSA is Hypericum perforatum L., commonly known as St. John s wort. In traditional folk medicine, oily extracts of St. John s wort are used for topical treatment of wounds, bums and myalgia [39]. The lipophilic phloroglucin-derivative hyperforin. Fig. 3, has antibacterial effects and has been shown to inhibit the growth of MRSA at a concentration of 1 (ig/ml [39]. Thus, investigating known plants based on their historical medical (ethnomedical) use is a potentially useful means of discovering new alternative antimicrobial agents. 

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